Reimbursement for PROKER®

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Topic: Amniotic Membrane

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Updated: 08/08/2022

This FAQ addresses the following:

What is PROKERA®?
What CPT code describes administration of Prokera?
Does Medicare cover placement of a Prokera biologic corneal bandage?
What are the indications for Prokera?
What is the Medicare allowed amount for physicians performing 65778?
What does Medicare allow as a facility fee for 65778?
Does Medicare pay for the supply of Prokera separately?
What is the postoperative surgical period for 65778?
How am I reimbursed for using Prokera during the postoperative period of another procedure?
How is Prokera reimbursed when used after corneal surgery?

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The reimbursement information is provided by Corcoran Consulting Group based on publicly available information from CMS, the AMA, and other sources. The reader is strongly encouraged to review federal and state laws, regulations, code sets, and official instructions promulgated by Medicare and other payers. This document is not an official source nor is it a complete guide on reimbursement. Although we believe this information is accurate at the time of publication, the reader is reminded that this information, including references and hyperlinks, changes over time, and may be incorrect at any time following publication.

© 2026 Corcoran Consulting Group. A Subsidiary of Medical Consulting Group, LLC. All rights reserved. No part of this publication may be reproduced or distributed in any form or by any means, or stored in a retrieval system, without the written permission of the publisher. CPT is a registered trademark of the American Medical Association.